Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)
Phone: +49 351 210-2542
Anastasia Solomatina is a PhD student at the MOSAIC Group since October 2015. She is a Russian citizen, born in Krasnodar, Russia, in 1988.
From 2006 until 2011, Anastasia studied Biochemical Physics at the Orenburg State University (Russia). During that time she was supported by a Rector’s scholarship for successful students, and she was also named the “Best student of Orenburg State University”. She graduated with a Diploma (equiv. M.Sc.) in 2011.
Following her studies in Russia, Anastasia pursued an M.Sc. in Nanobiophysics at the BIOTEC of TU Dresden, which she completed in 2014. She did her Masters thesis at Max Planck Institute of Molecular Cell Biology and Genetics under the supervision of Dr. Iva Tolic. Her thesis focused on investigating the mitotic spindle structure and studying forces that are acting during metaphase. Throughout her studies, Anastasia was financially supported by the Association of Friends and Sponsors of TU Dresden.
In October 2013, Anastasia participated in the Biomolecular Design Competition (BIOMOD) organized by Wyss Institute of Harvard University, MA, USA. Her team NANORMOUS scored second rank and was awarded the silver medal. The competition project “Smart Nanoreactor” presented a new drug-delivery system, experimentally proven to be technologically feasible.
In the MOSAIC Group, Anastasia is working on simulating endosome tethering and intracellular trafficking and sorting. She investigates the mechanisms and algorithms underlying sub-cellular polarity and domain formation of tethering complexes on the surface of endosomes that ultimately explain the directionality of transport.
A Word from Anastasia...
My motivation for research is driven by the famous Richard Feynman quote: “What I can not create, I do not understand”. I am curious about understanding biological systems using an in silico reconstitution approach. Like a biochemist, I create a system by adding known constituents into a model, simulate it, and analyze the output. Also, like an experimentalist, I can change the geometry of my system. But in in silico reconstitution I have full control over the interaction mechanisms between the constituents. I develop and use this framework to understand the self-organization of the endocytic system in cells.